Spectroscopic Determination of Functionalized Active Principles from Coleus aromaticus Benth Leaf Extract Using Ionic Liquids

Green chemistry for plant extraction of active principles is the main interest of many researchers concerned with climate change. While classical organic solvents are detrimental to our environment, greener alternatives to ionic liquids are very promising for sustainable organic chemistry. This study focused on the determination of functional groups observed in the main constituents from the ionic liquid extracts of Coleus aromaticus Benth leaves using FT-IR Spectroscopy. Moreover, this research aimed to determine the best ionic liquid that can separate functionalized plant constituents from the leaves Coleus aromaticus Benth using Fourier Transform Infrared Spectroscopy. Coleus aromaticus Benth leaf extract in different ionic liquids, elucidated pharmacologically important functional groups present in major constituents of the plant, namely, rosmarinic acid, caffeic acid and chlorogenic acid. In connection to distinctive appearance of functional groups in the spectrum and highest % transmittance, potassium chloride-glycerol is the best ionic liquid for green extraction.





References:
[1] Potdar, M., Kelso, G., Schwarz, L., Zhang, C., and Hearn, M., (2015): Recent Developments in Chemical Synthesis with Biocatalysts in Ionic Liquids, Molecules 2015, 20, 16788-16816.
[2] Chemat, F., Vian, M. A., and Cravotto, G., (2012): Green Extraction of Natural Products: Concept and Principles, Int. J. Mol. Sci. 2012, 13, 8615-8627.
[3] Salminen, E., Virtanen P., and Mikkola, J., (2014): Alkaline Ionic Liquids Applied In Supported Ionic Liquid Catalyst For Selective Hydrogenation of Citral to Citronellal, Frontiers in Chemistry, February 2014, Volume 2, Article 3.
[4] Ghandi, K., (2014): A Review of Ionic Liquids, Their Limits and Applications, Green and Sustainable Chemistry, 2014, 4, 44-53.
[5] Guolin, H., Jeffrey, S., Kai, Z., and Xiaolan, H., (2012): Application of Ionic Liquids in the Microwave-Assisted Extraction of Pectin from Lemon Peels, Journal of Analytical Methods in Chemistry, Volume 2012, Article ID 302059, 8 pages.
[6] Diaz-Alvarez, A., and Cadierno, Victorio, (2013): Glycerol: A promising Green Solvent and Reducing Agent for Metal-Catalyzed Transfer Hydrogenation Reactions and Nanoparticles Formation, Appl. Sci., 3, 55-69.
[7] Ramya, B., Ganesh, P. and Kumar, R., (2012): Phytochemical Screening of Coleus aromaticus and Leucas aspera and Their Antibacterial Activity against Enteric Pathogens, International Journal of Pharmaceutical & Biological Archives, 3(1):162-166.