Microorganisms Isolated from Surgical Wounds Infection and Treatment with Different Natural Products and Medications
Surgical site infections (SSIs) are the most common
nosocomial infection in surgical patients resulting in significant
increases in postoperative morbidity and mortality. The commonly
causative bacteria developed resistance to virtually all antibiotics
available. The aim of this study was to isolation and identification the
most common bacteria that cause SSIs in Medical Research Institute,
and to compare their sensitivity to selected group of antibiotics and
natural products (garlic, oregano, olive, and Nigella sativa oils). The
isolated pathogens collected from infected surgical wounds were
identified, and their sensitivities to the antibiotics commonly
available for clinical use, and also to the different concentrations of
the used natural products were investigated. The results indicate to
the potential therapeutic effect of the tested natural products in
treatment of surgical wound infections.
[1] D.L. Malone, T. Genuit, J.K. Tracy, C. Gannon, L.M. Napolitano,
"Surgical site infection: reanalysis of risk factors,".J. Surg. Res., vol.
103, pp. 89-95, 2002.
[2] W. Bereket, K. Hemalatha, B. Getenet, T. Wondwossen, A. Solomon, A.
Zeynudin, S. Kannan, "Update on bacterial nosocomial infections," Eur.
Rev. Med. Pharmacol. Sci., vol. 16, pp. 1039-1044, 2012.
[3] A. Röhrborn, H. Wacha, U. Schöffel, A. Billing, P. Aeberhard, B.
Gebhard, I. Böcker, V. Sch├ñfer, C. Ohmann, "Coverage of enterococci
in community acquired secondary peritonitis: results of a randomized
trial," Surg. Infect. (Larchmt), vol. 1, pp. 95-107, 2000.
[4] R. Podschun, H. Acktun, J. Okpara, O. Linderkamp, U. Ullmann, M.
Borneff-Lipp, "Isolation of Klebsiella planticola from newborns in a
neonatal ward," J. Clin. Microbiol., Vol. 36, pp. 2331-2332, 1998.
[5] H. Fazeli, R. Akbari, S. Moghim, T. Narimani, M.R. Arabestani, A.R.
Ghoddousi, "Pseudomonas aeruginosa infections in patients, hospital
means, and personnel's specimens," J. Res. Med. Sci., vol. 17, pp. 332-
337, 2012.
[6] K. Rit, R. Saha R, "Multidrug-resistant acinetobacter infection and their
susceptibility patterns in a tertiary care hospital," Niger. Med. J., vol. 53,
pp. 126-128, 2012.
[7] D.R. Schaberg, D.H. Culver, R.P. Gaynes, "Major trends in the
microbial etiology of nosocomial infection," Am. J. Med., vol. 91, pp.
72S-75S, 1991.
[8] R. Schwarzkopf, T.A. Russell, M. Shea, J.D. Slover, "Correlation
between nutritional status and Staphylococcus colonization in hip and
knee replacement patients," Bull. N.Y.U. Hosp. Jt. Dis., vol. 69, pp. 308-
311, 2011.
[9] H.M. El-Fatatry, "Isolation and structure assignment of an antimicrobial
principle from the volatile oil of Nigella sativa L. seeds," Pharmazie,
vol. 30, pp. 109-111, 1975.
[10] R. Di Pasqua, V. De Feo, F. Villani, G. Mauriello, "In vitro
antimicrobial activity of essential oils from Mediterranean apiaceae,
Verbenaceae and Lamiaceae against food borne pathogens and spoilage
bacteria," Ann. Microbiol., vol. 55, pp. 139-143, 2005.
[11] S. Cicerale, L. Lucas, R. Keast, "Biological activities of phenolic
compounds present in virgin olive oil," Int. J. Mol. Sci., vol. 11, pp. 458-
479, 2010.
[12] A. Ivanova, B. Mikhova, H. Najdenski, I. Tsvetkova, I. Kostova,
"Chemical composition and antimicrobial activity of wild garlic Allium
ursinum of Bulgarian origin," Nat. Prod. Commun., vol. 4, pp. 1059-
1062, 2009.
[13] A.W. Bauer, W.M.M. Kirby, J.C. Sherris, M. Turck, "Antibiotic
susceptibility testing by a standardized single disk method," Am. J.
Clin. Pathol., vol. 36, pp. 493-496, 1966.
[1] D.L. Malone, T. Genuit, J.K. Tracy, C. Gannon, L.M. Napolitano,
"Surgical site infection: reanalysis of risk factors,".J. Surg. Res., vol.
103, pp. 89-95, 2002.
[2] W. Bereket, K. Hemalatha, B. Getenet, T. Wondwossen, A. Solomon, A.
Zeynudin, S. Kannan, "Update on bacterial nosocomial infections," Eur.
Rev. Med. Pharmacol. Sci., vol. 16, pp. 1039-1044, 2012.
[3] A. Röhrborn, H. Wacha, U. Schöffel, A. Billing, P. Aeberhard, B.
Gebhard, I. Böcker, V. Sch├ñfer, C. Ohmann, "Coverage of enterococci
in community acquired secondary peritonitis: results of a randomized
trial," Surg. Infect. (Larchmt), vol. 1, pp. 95-107, 2000.
[4] R. Podschun, H. Acktun, J. Okpara, O. Linderkamp, U. Ullmann, M.
Borneff-Lipp, "Isolation of Klebsiella planticola from newborns in a
neonatal ward," J. Clin. Microbiol., Vol. 36, pp. 2331-2332, 1998.
[5] H. Fazeli, R. Akbari, S. Moghim, T. Narimani, M.R. Arabestani, A.R.
Ghoddousi, "Pseudomonas aeruginosa infections in patients, hospital
means, and personnel's specimens," J. Res. Med. Sci., vol. 17, pp. 332-
337, 2012.
[6] K. Rit, R. Saha R, "Multidrug-resistant acinetobacter infection and their
susceptibility patterns in a tertiary care hospital," Niger. Med. J., vol. 53,
pp. 126-128, 2012.
[7] D.R. Schaberg, D.H. Culver, R.P. Gaynes, "Major trends in the
microbial etiology of nosocomial infection," Am. J. Med., vol. 91, pp.
72S-75S, 1991.
[8] R. Schwarzkopf, T.A. Russell, M. Shea, J.D. Slover, "Correlation
between nutritional status and Staphylococcus colonization in hip and
knee replacement patients," Bull. N.Y.U. Hosp. Jt. Dis., vol. 69, pp. 308-
311, 2011.
[9] H.M. El-Fatatry, "Isolation and structure assignment of an antimicrobial
principle from the volatile oil of Nigella sativa L. seeds," Pharmazie,
vol. 30, pp. 109-111, 1975.
[10] R. Di Pasqua, V. De Feo, F. Villani, G. Mauriello, "In vitro
antimicrobial activity of essential oils from Mediterranean apiaceae,
Verbenaceae and Lamiaceae against food borne pathogens and spoilage
bacteria," Ann. Microbiol., vol. 55, pp. 139-143, 2005.
[11] S. Cicerale, L. Lucas, R. Keast, "Biological activities of phenolic
compounds present in virgin olive oil," Int. J. Mol. Sci., vol. 11, pp. 458-
479, 2010.
[12] A. Ivanova, B. Mikhova, H. Najdenski, I. Tsvetkova, I. Kostova,
"Chemical composition and antimicrobial activity of wild garlic Allium
ursinum of Bulgarian origin," Nat. Prod. Commun., vol. 4, pp. 1059-
1062, 2009.
[13] A.W. Bauer, W.M.M. Kirby, J.C. Sherris, M. Turck, "Antibiotic
susceptibility testing by a standardized single disk method," Am. J.
Clin. Pathol., vol. 36, pp. 493-496, 1966.
@article{"International Journal of Medical, Medicine and Health Sciences:63314", author = "Amany S. Youssef and Suzan A.M. El Feky and Samy A. El-Asser and Rasha A.M. Abd Allah", title = "Microorganisms Isolated from Surgical Wounds Infection and Treatment with Different Natural Products and Medications", abstract = "Surgical site infections (SSIs) are the most common
nosocomial infection in surgical patients resulting in significant
increases in postoperative morbidity and mortality. The commonly
causative bacteria developed resistance to virtually all antibiotics
available. The aim of this study was to isolation and identification the
most common bacteria that cause SSIs in Medical Research Institute,
and to compare their sensitivity to selected group of antibiotics and
natural products (garlic, oregano, olive, and Nigella sativa oils). The
isolated pathogens collected from infected surgical wounds were
identified, and their sensitivities to the antibiotics commonly
available for clinical use, and also to the different concentrations of
the used natural products were investigated. The results indicate to
the potential therapeutic effect of the tested natural products in
treatment of surgical wound infections.", keywords = "Surgical wounds, multi-resistant bacteria, bacterial sensitivity, natural oils.", volume = "7", number = "6", pages = "313-4", }