Abstract: Bioprocesses are appreciated as difficult to control because their dynamic behavior is highly nonlinear and time varying, in particular, when they are operating in fed batch mode. The research objective of this study was to develop an appropriate control method for a complex bioprocess and to implement it on a laboratory plant. Hence, an intelligent control structure has been designed in order to produce biomass and to maximize the specific growth rate.
Abstract: Despite the extensive use of eLearning systems, there
is no consensus on a standard framework for evaluating this kind of
quality system. Hence, there is only a minimum set of tools that can
supervise this judgment and gives information about the course
content value. This paper presents two kinds of quality set evaluation
indicators for eLearning courses based on the computational process
of three known metrics, the Euclidian, Hamming and Levenshtein
distances. The “distance" calculus is applied to standard evaluation
templates (i.e. the European Commission Programme procedures vs.
the AFNOR Z 76-001 Standard), determining a reference point in the
evaluation of the e-learning course quality vs. the optimal concept(s).
The case study, based on the results of project(s) developed in the
framework of the European Programme “Leonardo da Vinci", with
Romanian contractors, try to put into evidence the benefits of such a
method.
Abstract: Bioprocesses are appreciated as difficult to control because their dynamic behavior is highly nonlinear and time varying, in particular, when they are operating in fed batch mode. The research objective of this study was to develop an appropriate control method for a complex bioprocess and to implement it on a laboratory plant. Hence, an intelligent control structure has been designed in order to produce biomass and to maximize the specific growth rate.
Abstract: An immunomodulator bioproduct is prepared in a
batch bioprocess with a modified bacterium Pseudomonas
aeruginosa. The bioprocess is performed in 100 L Bioengineering
bioreactor with 42 L cultivation medium made of peptone, meat
extract and sodium chloride. The optimal bioprocess parameters were
determined: temperature – 37 0C, agitation speed - 300 rpm, aeration
rate – 40 L/min, pressure – 0.5 bar, Dow Corning Antifoam M-max.
4 % of the medium volume, duration - 6 hours. This kind of
bioprocesses are appreciated as difficult to control because their
dynamic behavior is highly nonlinear and time varying. The aim of
the paper is to present (by comparison) different models based on
experimental data.
The analysis criteria were modeling error and convergence rate.
The estimated values and the modeling analysis were done by using
the Table Curve 2D.
The preliminary conclusions indicate Andrews-s model with a
maximum specific growth rate of the bacterium in the range of
0.8 h-1.