Abstract: Today, the treatment of cancer, in a relatively short
period, with minimum adverse effects is a great concern for
oncologists. In this paper, based on a recently used mathematical
model for cancer, a guideline has been proposed for the amount
and duration of drug doses for cancer treatment by immunotherapy.
Dynamically speaking, the mathematical ordinary differential
equation (ODE) model of cancer has different equilibrium points;
one of them is unstable, which is called the no tumor equilibrium
point. In this paper, based on the number of tumor cells an
intelligent soft computing controller (a combination of fuzzy logic
controller and genetic algorithm), decides regarding the amount
and duration of drug doses, to eliminate the tumor cells and
stabilize the unstable point in a relatively short time. Two different
immunotherapy approaches; active and adoptive, have been studied
and presented. It is shown that the rate of decay of tumor cells is
faster and the doses of drug are lower in comparison with the result
of some other literatures. It is also shown that the period of
treatment and the doses of drug in adoptive immunotherapy are
significantly less than the active method. A recommendation to
oncologists has also been presented.
Abstract: In this paper a comprehensive model of a fossil fueled
power plant (FFPP) is developed in order to evaluate the
performance of a newly designed turbine follower controller.
Considering the drawbacks of previous works, an overall model is
developed to minimize the error between each subsystem model
output and the experimental data obtained at the actual power plant.
The developed model is organized in two main subsystems namely;
Boiler and Turbine. Considering each FFPP subsystem
characteristics, different modeling approaches are developed. For
economizer, evaporator, superheater and reheater, first order models
are determined based on principles of mass and energy conservation.
Simulations verify the accuracy of the developed models. Due to the
nonlinear characteristics of attemperator, a new model, based on a
genetic-fuzzy systems utilizing Pittsburgh approach is developed
showing a promising performance vis-à-vis those derived with other
methods like ANFIS. The optimization constraints are handled
utilizing penalty functions. The effect of increasing the number of
rules and membership functions on the performance of the proposed
model is also studied and evaluated. The turbine model is developed
based on the equation of adiabatic expansion. Parameters of all
evaluated models are tuned by means of evolutionary algorithms.
Based on the developed model a fuzzy PI controller is developed. It
is then successfully implemented in the turbine follower control
strategy of the plant. In this control strategy instead of keeping
control parameters constant, they are adjusted on-line with regard to
the error and the error rate. It is shown that the response of the
system improves significantly. It is also shown that fuel consumption
decreases considerably.
Abstract: In order to meet the limits imposed on automotive
emissions, engine control systems are required to constrain air/fuel
ratio (AFR) in a narrow band around the stoichiometric value, due to
the strong decay of catalyst efficiency in case of rich or lean mixture.
This paper presents a model of a sample spark ignition engine and
demonstrates Simulink-s capabilities to model an internal combustion
engine from the throttle to the crankshaft output. We used welldefined
physical principles supplemented, where appropriate, with
empirical relationships that describe the system-s dynamic behavior
without introducing unnecessary complexity. We also presents a PID
tuning method that uses an adaptive fuzzy system to model the
relationship between the controller gains and the target output
response, with the response specification set by desired percent
overshoot and settling time. The adaptive fuzzy based input-output
model is then used to tune on-line the PID gains for different
response specifications. Experimental results demonstrate that better
performance can be achieved with adaptive fuzzy tuning relative to
similar alternative control strategies. The actual response
specifications with adaptive fuzzy matched the desired response
specifications.